Tag Archives: disease

Dot Earth Blog: As W.H.O. Weighs Zika as ‘Emergency,’ a Look at the World’s Failed Mosquito Policies

Areas stricken in Zika virus outbreak were once free of the mosquito that carries this and other dangerous diseases. Link:   Dot Earth Blog: As W.H.O. Weighs Zika as ‘Emergency,’ a Look at the World’s Failed Mosquito Policies ; ; ;

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Dot Earth Blog: As W.H.O. Weighs Zika as ‘Emergency,’ a Look at the World’s Failed Mosquito Policies

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As W.H.O. Weighs Zika as ‘Emergency,’ a Look at the World’s Failed Mosquito Policies

Areas stricken in Zika virus outbreak were once free of the mosquito that carries this and other dangerous diseases. More here:  As W.H.O. Weighs Zika as ‘Emergency,’ a Look at the World’s Failed Mosquito Policies ; ; ;

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As W.H.O. Weighs Zika as ‘Emergency,’ a Look at the World’s Failed Mosquito Policies

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The FDA Is Giving New Cancer Treatments a Break

Mother Jones

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For a variety of reasons, I’ve never spent much time on the internet reading or conversing about multiple myeloma. A few days ago, however, I had reason to think I should educate myself a bit more. Among other things, I discovered that within the space of two weeks in the second half of November, the FDA had approved no fewer than three new treatments. I suppose this can’t be anything but coincidence, but then another coincidence piled on top of that: a New York Times piece about Richard Pazdur, the oncology chief at the FDA. Three years ago, his wife was diagnosed with ovarian cancer:

In her struggle with cancer and ultimately her death in November, Ms. Pazdur had a part, her husband and a number of cancer specialists now say, in a profound change at the F.D.A.: a speeding up of the drug approval process. Ms. Pazdur’s three-year battle with cancer was a factor, they say, in Dr. Pazdur’s willingness to swiftly approve risky new treatments and passion to fight the disease that patient advocates thought he lacked.

….Since Ms. Pazdur learned she had ovarian cancer in 2012…the average decision time on drugs by Dr. Pazdur’s oncology group has come down to five months from six months….“I have a much greater sense of urgency these days,” Dr. Pazdur, 63, said in an interview. “I have been on a jihad to streamline the review process and get things out the door faster. I have evolved from regulator to regulator-advocate.”

Many factors are driving him, he continued. “Was Mary’s illness one of them? Yes,” he said. But in 2012, he added, Congress also passed a law that gave the F.D.A. more money and a new pathway to work more closely with drug makers when a medicine may save lives. Another important change in the same period, he said, was a surge in advances in genetic research that made some medications more effective and easier to test.

“The drugs simply got better,” Dr. Pazdur said.

Again, I suppose this is mostly coincidence. But I still wonder if Mary Pazdur’s cancer played a role in all these multiple myeloma treatments getting approved recently? If so, her death may eventually play a role in saving—or extending—my life. A butterfly flaps its wings….

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The FDA Is Giving New Cancer Treatments a Break

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How 19 Big-Name Corporations Plan to Make Money Off the Climate Crisis

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Think weapons, air conditioners, and ice cream, for starters. New York officials tour flood damage in a Sikorsky Black Hawk helicopter in 2011. Hans Pennink/AP Climate change will have some pretty terrifying consequences. Experts have predicted everything from deadly heat waves and devastating floods to falling crop production and even increased political instability and violence. But according to some of the world’s biggest companies, these future disasters could also present lucrative business opportunities. In a remarkable series of documents submitted to a London-based nonprofit called CDP, big-name corporations describe global warming as a chance to sell more weapons systems to the military, more air conditioners to sweltering civilians, and more medications to people afflicted by tropical diseases. CDP, which stands for “Carbon Disclosure Project,” asks companies all over the world to disclose information about their greenhouse gas emissions and how the changing climate will impact their operations. Each year, thousands of companies send in responses. Below, we’ve compiled a list of some of the most striking—and, in some cases, disturbing—scenarios laid out by those businesses. It’s important to keep in mind that these companies aren’t rooting for catastrophic warming. In the same documents, they outline huge risks that climate change poses to humanity—and to their profits. Many of them have also taken significant steps to reduce their own carbon footprints. Still, the fact that corporations have spent so much time thinking about the business opportunities that could emerge as the world warms underscores just how colossal an effect climate change is going to have on our lives. Defense and border surveillance Embed from Getty Images Republicans have recently mocked President Barack Obama and Sen. Bernie Sanders for saying climate change poses a national security threat. But Democratic politicians aren’t the only ones making this connection. In 2014, the CNA Military Advisory Board, a group of retired US generals and admirals, warned that the impacts of global warming “will serve as catalysts for instability and conflict.” Saab, a Swedish defense firm (and former parent company of the struggling automaker), agrees. In its CDP submission, the company cites the CNA report and adds that climate change could “induce changes in natural resources e.g. water, oil etc., which may result in conflicts within already unstable countries” as well as illegal deforestation, fishing, and drug smuggling. Saab sees these dangers as a business opportunity that will result in an “increased market for civil and military security solutions.” As an example, the company points to its Erieye Radar System, which “works in a dense hostile electronic warfare environment” and is “capable of identifying friends or foes.” Raytheon, the Massachusetts-based defense contractor, warned in a 2012 CDP document that climate change might “cause humanitarian disasters, contribute to political violence, and undermine weak governments.” The company wrote that it expects to see “demand for its military products and services as security concerns may arise as results of droughts, floods, and storm events occur as a result of climate change.” Connecticut-based United Technologies Corporation cites arguments that a devastating drought contributed to instability in Syria. The company notes that helicopters made by its Sikorsky business (which has since been sold to Lockheed Martin) were “deployed during population dislocations and humanitarian crises,” and that last year it provided support to the US military’s efforts to “mitigate population dislocations in Syria.” Cobham, a British corporation that manufacturers surveillance systems, stated in a 2013 CDP document that “changes to countries [sic] resources and habitability could increase the need for border surveillance due to population migration.” Security from “social unrest” G4S provides security for the enormous refugee camps outside Dadaab, Kenya. Many of the camps’ residents fled conflict and drought. Jerome Delay/AP Private security firms also see opportunities in climate change. G4S, a London-based corporation that operates around the globe, told CDP that extreme weather is a potential source of business. The company deployed hundreds of security officers to protect its clients following Hurricane Katrina, and it sent officers throughout the Northeast following Superstorm Sandy. G4S also sees financial opportunities in responding to humanitarian disasters such as droughts and famines in the developing world. The company currently provides security for refugee camps in Kenya that are home to hundreds of thousands of people, including many who have fled conflict and drought. G4S says the United Nations “has projected that we [the planet] will have 50 million environmental refugees.” (The United Nations appears to have backed off that particular prediction; according to its Intergovernmental Panel on Climate Change [PDF], “there are no robust global estimates of future displacement.”) Securitas, a Stockholm-based firm that owns the fabled Pinkerton agency, also provided security in the aftermath of Katrina. That company says extreme weather linked to climate change will increase demand for its services “when properties…need to be protected from looting, burglary and social unrest.” Monitoring, Responding to, and Rebuilding From Extreme Weather Embed from Getty Images According to Raytheon, the possible impacts of climate change—including hurricanes, tornadoes, severe storms, and rising seas—could present opportunities to sell the company’s “weather satellites services, radar and sensing technologies, disaster response, homeland security, and emergency response communications, as well as alternative energy technologies.” Cobham anticipates opportunities to supply cameras to monitor flash floods, “large antennas” for extreme weather conditions, and emergency communications systems for “areas where severe storms have destroyed communications infrastructure.” 3M, the Minnesota-based manufacturing company, says it sells a number of products that can be used to protect buildings during extreme weather and to rebuild after a storm. Shipping Lanes and Travel Embed from Getty Images One of the most striking climate developments in recent years has been the opening of Arctic shipping lanes that were once obstructed by sea ice year-round. Hanjin, a major South Korean shipping company, acknowledged in a 2014 CDP document that a new polar route would be a “tragic consequence” of climate change. But, the company added, Arctic melting would also have environmental and financial benefits: It would allow the shipping industry to “drastically reduce CO2 emissions and cut transit time by 1/3.” Global warming could have some benefits for companies that specialize in transporting tourists, as well. According to Carnival, “change in mean temperatures could open up new routes and ports” for its cruise ships, while “change in precipitation [might] make some ports more attractive.” Drilling for more oil Embed from Getty Images Energy companies have long viewed melting Arctic ice as an opportunity to extract once-inaccessible oil and gas. That hasn’t worked out well so far. In September, Royal Dutch Shell announced that it was ending its costly Arctic exploration project. But Chevron is still optimistic. “Should the current trend in global warming be sustained, both access to and the economics of Chevron’s offshore oil and gas production in the arctic could potentially improve,” states the California-based oil company in its CPD disclosure. “The greatest effects will be associated with an extension to the summer operating period which will tend initially to favor access to and the cost of exploration operations in many arctic basins.” Protection From Deadly Heat Waves Embed from Getty Images In a report last year, a panel co-chaired by former New York Mayor Michael Bloomberg, billionaire environmentalist Tom Steyer, and former Treasury Secretary Henry Paulson warned of risks posed by hotter temperatures: By the middle of this century, the average American will likely see 27 to 50 days over 95°F each year—two to more than three times the average annual number of 95°F days we’ve seen over the past 30 years. By the end of this century, this number will likely reach 45 to 96 days over 95°F each year on average. That’s an opportunity for United Technologies, which—in addition to its defense products—makes air conditioning, refrigeration, and energy efficiency systems. “Annually, extreme heat events kill more Americans than any other environmentally related events, and an increase in extreme heart [sic] events as a result of climate change is forecast for many parts of the world,” the company states. “UTC believes changes in temperature extremes will result in a need for more energy efficient building and other infrastructure, especially chillers and cooling units…We anticipate this demand to be global, with strong increases in tropical and some temperate zones.” According to UTC, “air conditioner sales have increased more than 20% per decade in the developing world 1990 – 2010 in response to increasing temperatures and increasing wealth.” UTC believes these trends could lead to $5 billion in new demand over the next two decades. Halliburton sees related opportunities. The oilfield services company states that it could see increased revenue from the additional energy resources needed for “increase[d] cooling and/or heating.” Combating Crop Failure and Hunger Embed from Getty Images Experts have warned that rising temperatures and changing rainfall patterns could reduce crop yields in vulnerable parts of the world, making it difficult to feed a growing population. Biotech companies are racing to develop products that will address this problem. Monsanto, for example, says its products could help farmers “meet increased food needs as available natural resources become more limited.” Bayer notes that its crop sciences division is using “chemical and modern plant breeding approaches” to address the agricultural damage expected to be caused by “an increased occurrence of extreme weather events such as floods, droughts, heat, cold and storms.” On the consumer side, the Campbell Soup Company identifies “increasing humanitarian demands” related to climate as a significant opportunity—one that will allow the company to “leverage its key assets to provide relief for such demands.” In addition to directly donating money and food to humanitarian causes, Campbell highlights a current program in which one of its brands donates one smoothie to a needy child for every four smoothies that it sells. According to the company, these types of promotions “can result in millions of dollars for the company.” Fighting Climate-Related Diseases Embed from Getty Images Climate change poses a number of serious public health risks, and the pharmaceutical industry has certainly noticed. Walmart, for instance, believes that it could experience growing demand for prescription medications due to “increases in pollen exposure or climate-change induced medical conditions.” (The retail giant is careful to note that it primarily views climate change, which a spokesperson calls an “urgent and pressing challenge,” as a risk.) Several drug companies believe that rising temperatures, changing precipitation patterns, and worsening extreme weather could increase the spread of tropical diseases that are transmitted by mosquitoes, such as malaria and dengue fever. In its CDP document, Bayer cites one estimate that climate change could result in 40 million to 60 million additional people being exposed [PDF] to these diseases. The company anticipates increased demand for its mosquito nets and other mosquito-control products, especially if malaria spreads to the developed world. GlaxoSmithKline also anticipates that climate change could affect demand for its anti-malarial products and notes that if the company’s “sales rose by 1% around £300m [about $446 million] would be added to our turnover.” A GSK spokesperson added, however, that the company is developing a malaria vaccine that it would offer to African children at a “not-for-profit price,” and that under some scenarios, climate change could actually reduce demand for the company’s products. Novartis, which makes several malaria and dengue drugs, points out that it has provided millions of doses to African health officials at a not-for-profit price. But, the company notes, “businesses selling these drugs will become more profitable if the diseases spread to more developed and richer countries.” A number of experts doubt that will happen, at least in the case of malaria. They argue that factors such as economic development and public health infrastructure are far more significant than climate in controlling malaria. Asked for clarification, a Novartis spokesperson stated that higher temperatures and increased extreme weather from climate change could “lead to large floods, social crises and challenges, which may allow vector diseases to spread further.” Still, he added, Novartis agrees that malaria is unlikely to spread in the developed world. Drug companies point to other health threats, as well. GSK warns that changing precipitation patterns and increased extreme weather events could “affect the spread of water-borne diseases” and respiratory and diarrheal illnesses, creating a need for “greater disease prevention and more patient treatments.” These problems could be especially serious in the poorest countries, according the GSK spokesperson. In its CDP submission, Merck says it is researching the negative impacts that higher temperatures could have on vaccines. Ice Cream! Austronesian Expeditions/Flickr Rising temperatures don’t just drive demand for air-conditioning units and better vaccines. According Nestlé, they can also boost sales of “refreshing products such as ice creams and bottled water.” Nestlé notes that in 2014, Earth experienced its hottest summer on record (until 2015, anyway) and that a number of the company’s local brands performed well that year. So how much of an impact does heat have? “Increased demand for bottled water and ice creams as a result of temperature increase can result in additional sales of CHF 100 million per year,” says Nestlé. In case you aren’t familiar with the exchange rate for Swiss francs, that’s about $100 million.

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How 19 Big-Name Corporations Plan to Make Money Off the Climate Crisis

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How 19 Big-Name Corporations Plan to Make Money Off the Climate Crisis

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The Shocking New Numbers on HIV in America

Mother Jones

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On the surface, the news about HIV in the United States sounds good. According to a new report from the Centers for Disease Control and Prevention, the diagnosis rate dropped 19 percent from 2005 to 2014—a dramatic decline. Among heterosexuals, new HIV diagnoses fell by 35 percent; among people who inject drugs, 63 percent; among women, 40 percent. And the CDC estimates that 87 percent of people with HIV know their status, representing a modest gain in testing and awareness.

Yet the trend toward steady diagnosis rates masks large disparities among men who have sex with men (MSM), who account for 67 percent of HIV-positive Americans. For black men in this group, already disproportionately affected by HIV/AIDS, diagnoses rose 22 percent; for Latino men, they’ve increased almost a quarter, an increase likely attributable to more infections, not better testing, the CDC told The Verge.

The steepest increases in HIV diagnoses have occurred among black and Latino gay youth between the ages of 13 and 24: 5,540 teens received the diagnosis in 2014, a rise of 87 percent since 2005.

Diagnosis stats tell only part of the story: More than two-thirds of transmissions come from people who know that they are HIV positive but are not receiving care. Just 39 percent of people with HIV are being treated for it; only 30 percent have a reduced viral load.

Last Tuesday, CDC director Thomas Frienden published an essay with Jonathan Mermin, the government’s HIV/AIDS prevention chief, warning that the United States may still lose the fight against AIDS. “Hundreds of thousands of people with diagnosed HIV infection are not receiving care,” they wrote. “These people account for most new HIV transmissions in the United States.”

In July, the government released a list of targets for 2020 to measure progress in the fight against HIV/AIDS. They included reducing new diagnoses by at least 25 percent, boosting the percentage of HIV-positive people receiving medical care to 90 percent, and increasing the percentage with suppressed viral loads to 80 percent.

The techniques to fight those battles exist. One promising preventative therapy involves treating uninfected but at-risk people with a combination of anti-HIV drugs known as Truvada. And in May, the CDC halted a study on the effects of early treatment because its benefits were so obvious.

But just because the drugs exist doesn’t mean that people can access them. Last year, CDC researchers highlighted how difficult it can be for some minority communities to receive health care and supportive services for HIV, and they called for better outreach from state and local health departments, community-based organizations, and individual health care providers.

“Faster progress depends on our collective ability to take full advantage of these tools in every community and every region of the country,” wrote the CDC researchers in the latest report. “We need to boldly address stigma, discrimination, and other social, economic, and structural issues that increase vulnerability to HIV and come between people and the care they need.”

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The Shocking New Numbers on HIV in America

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A Lot of People Are Telling Congress to Repeal Its Gag Order on Gun Violence Research

Mother Jones

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Even before today’s tragic shooting in San Bernardino, pressure was building in Washington to overturn an NRA-backed amendment that has barred federal research on gun violence for nearly 20 years. More than 2,000 physicians, dozens of Democratic lawmakers, and even the author of the amendment have all called on Congress to once again allow gun violence to be investigated as a public health issue.

On Wednesday, nine medical associations publicly urged Congress to overturn the so-called Dickey Amendment, which in 1996 effectively halted research by the Centers for Disease Control and Prevention (CDC) and the National Institutes of Health (NIH) into the causes of gun violence.

“Gun violence is a public health problem that kills 90 Americans a day,” Dr. Alice Chen, the executive director of Doctors for America, said in a statement. “Physicians believe it’s time to lift this effective ban and fund the research needed to save lives.”

Tacked onto a 1996 appropriations bill, the Dickey Amendment was pushed through Congress by Republican legislators under substantial pressure from the National Rifle Association, as the amendment’s author, former Rep. Jay Dickey (R-Ark.), admitted in a 2012 op-ed in The Washington Post that he co-authored. Dickey wrote that the lack of research by the NIH and CDC had resulted in a troubling information gap: “US scientists cannot answer the most basic question: What works to prevent firearm injuries? We don’t know whether having more citizens carry guns would decrease or increase firearm deaths; or whether firearm registration and licensing would make inner-city residents safer or expose them to greater harm.”

The doctors are not alone in calling for the amendment to be overturned: late last month, dozens of House Democrats made a similar plea to renew federal research on gun violence. “We dedicate $240 million a year on traffic safety research, more than $233 million a year on food safety, and $331 million a year on the effects of tobacco, but almost nothing on firearms that kill 33,000 Americans annually,” they wrote in a letter to senior representatives in charge of appropriations. A few weeks before that, Rep. Mike Honda (D-Calif.) submitted a bill called the Gun Violence Research Act with the express purpose of “helping identify and treat those prone to committing mass shootings.”

Dickey himself has repeatedly urged Congress to overturn the provision that bears his name. In a letter published Wednesday by Rep. Mike Thompson (D-Calif.), chairman of the House Gun Violence Prevention Task Force, Dickey wrote, “Doing nothing is no longer an acceptable solution.”

“I commend Jay Dickey for taking this stand,” Thompson wrote in response. “As gun owners, we want to protect the Second Amendment. But at the same time, we recognize the fact that we can safeguard those rights while also allowing our expert scientists to conduct research on how to best prevent gun violence.”

A Mother Jones investigation published this summer found that gun violence costs the US a staggering $229 billion every year.

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A Lot of People Are Telling Congress to Repeal Its Gag Order on Gun Violence Research

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These Senators Want To Break the NRA’s Stranglehold on Gun Violence Research

Mother Jones

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For years, Congress has blocked funding for research into the impacts of guns on public health. On Wednesday morning, twenty Senate Democrats demanded a necessary first step to upset that status quo, by asking the Government Accountability Office to audit what health programs exist to make guns safer.

“With more than 300 million guns in American homes, we write to request that the Government Accountability Office (GAO) conduct a study to assess the efficacy of public health and safety programs designed to impact gun safety, including the storage and security of guns in households throughout our country,” they wrote in a letter to Gene Dorado, Comptroller General of the United States.

The senators note that other federal public health campaigns, such as those to reduce drunk driving and smoking, have been hugely effective. But for nearly 20 years, Congress has pushed the Centers for Disease Control and Prevention (CDC) to steer clear of firearms violence research. “I’m sorry, but a gun is not a disease,” said former House Speaker John Boehner this summer, after the House Appropriations Committee voted to block funding on gun research to the CDC.

“Prevention of gun deaths and injuries should be an essential component of the federal government’s commitment to public heath and safety along with other efforts such as background checks on gun purchases and closing other gun loopholes,” the senators wrote.

A Mother Jones investigation, inspired by the lack of research on the matter, found that gun violence costs Americans a whopping $229 billion each year. A Washington Post investigation found that Americans are getting shot by toddlers on a weekly basis.

The senators’ request was lauded by gun control advocacy groups. “The American people have had enough of gun violence and this is an important step,” said Dan Gross, president of the Brady Campaign to Prevent Gun Violence.

Read the full letter below:

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Letter to GAO on Gun Safety (PDF)

Letter to GAO on Gun Safety (Text)

Watch part of our investigation into the costs of gun violence here:

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These Senators Want To Break the NRA’s Stranglehold on Gun Violence Research

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Heroin’s Death Toll Reaches Another Gruesome Landmark

Mother Jones

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For the first time in Virginia’s history, more people died last year from overdoses on heroin and prescription opioids than from automobile accidents. The state joins 35 others that have seen heroin and opioid deaths eclipse traffic deaths, in an alarming trend that has begun to draw attention on the presidential campaign trail.

In 2014, 728 people succumbed to heroin or opioid-related overdoses, compared to 700 people who died in car crashes. A year earlier, the statistical comparison was flipped, with the highway death toll in Virginia at 741, compared to 661 deaths from drug overdoses. The year before that, in 2012, the numbers were even more skewed toward automobile accidents, as 750 traffic deaths trumped the 504 drug overdoses in the state.

As the rate of traffic deaths drops—those 700 deaths are the fewest in a decade—the heroin overdose rate continues to climb. According to the office of Virginia Attorney General Mark Herring, fatal heroin and prescription drug overdoses have increased by 57% in the last five years alone.

“This heroin and prescription drug epidemic is a public health issue, a public safety and law enforcement issue, and most importantly, it’s a family issue,” Herring’s office stated in a press release last week. “The rising and tragic death toll adds a dose of reality and a sense of urgency to our efforts and those of our local, state and federal partners.”

The rise in fatal overdoses is not limited to Virginia. In 36 states and Washington, DC, more people are dying from drug overdoses than from traffic incidents. According to the nonprofit Trust for America’s Health, more than 2 million Americans abuse prescription drugs, and the number of new heroin users has doubled in the past seven years. As opiates prescribed by physicians have become more expensive, people have turned to heroin, a cheaper option with similar effects. The Center for Disease Control reports that heroin deaths quadrupled between 2000 and 2013.

“They are addicted to prescription opiates because they are essentially the same chemical with the same effect on the brain as heroin,” CDC director Frieden said at a press conference in July. “Heroin costs roughly 5 times less than prescription opiates on the street.”

Although heroin and opioid deaths are climbing at an alarming rate, less than one percent of the US population abuses heroin, according to the CDC. That figure, however, does not include people in the military, homeless people, or prison inmates, so the true number may be higher.

Presidential candidates have had to field questions about the growing trend while on the campaign trail. At an August public forum in New Hampshire, Democratic front-runner Hillary Clinton expressed surprise at the prevalence of the problem.

“I have to confess—I was surprised,” Clinton said. “I did not expect that I would hear about drug abuse and substance abuse and other such challenges everywhere I went.”

In May, New Jersey Gov. Chris Christie signed a bill designed to stymie substance abuse, and a week later expressed his frustration at what he considered a correctable issue. “This is a treatable problem,” Christie said. “And we need to be talking about it and treating it like an illness, and not like some moral failure.”

Former Hewlett-Packard CEO Carly Fiorina, whose daughter died in 2009 after years of drug and alcohol abuse, argued against imprisoning people for their drug problems. “Drug addition shouldn’t be criminalized,” Fiorina told a group of reporters during a conference call in May. “We need to treat it appropriately.”

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Heroin’s Death Toll Reaches Another Gruesome Landmark

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Here Are Your Chances of Getting an Antibiotic-Resistant Infection After Surgery

Mother Jones

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An eye-opening study published today in The Lancet Infectious Diseases medical journal shows just how many people acquire antibiotic-resistant infections after common procedures: Up to half of infections after surgery and a quarter of infections after chemotherapy are caused by resistant bacteria—meaning that they are significantly more difficult, if not impossible, to treat.

“A lot of common surgical procedures and cancer chemotherapy will be virtually impossible if antibiotic resistance is not tackled urgently,” said Dr. Ramanan Laxminarayan, a study co-author and director of the Center for Disease Dynamics, Economics, and Policy. “All of us at some point have to get a surgery or a root canal or a transplant, or perhaps go through chemo at some point in our lives. But how well these turn out depends on how well the antibiotics used to keep infections away during surgery work.”

Infections during and after surgeries and chemotherapy are common, so it is standard practice to give these patients antibiotics. But as the drugs are overused or misused, antibiotic resistance rates have risen. The Lancet authors conducted a meta-analysis of literature reviews on the efficacy of antibiotics after 10 of the most common surgeries in the United States. They found antibiotic-resistant bacteria to be causing 39 percent of infections after cesarean sections, 51 percent of infections after pacemaker implants, and 27 percent of infections after blood cancer chemotherapy.

If the efficacy of antibiotics drops 30 percent—a rate that the authors see as realistic given the current overuse of antibiotics—then infections from surgeries and chemotherapies could result in 120,000 more infections and 6,300 more infection-related deaths each year in the United States.

Dr. Laxminarayan suggests a multipronged solution to the problem: Doctors need to be trained on when (and when not) to prescribe antibiotics and how to minimize infections after common surgeries. Americans need to stay up to date on vaccines in order to reduce the need for antibiotics in the first place. If you’re getting surgery, he says, choose hospitals and surgeons with low infection rates—hospitals are required to publicly report these numbers in many states. (More from the Centers for Disease Control and Prevention, here).

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Here Are Your Chances of Getting an Antibiotic-Resistant Infection After Surgery

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This Company Gave Away a Drug That Just Won the Nobel Prize and Helped Millions

Mother Jones

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Earlier today, the Nobel committee awarded its renowned prize for medicine to the discoverers of two anti-parasitic drugs — one that fights malaria and one that treats two lesser-known devastating diseases.

The latter, ivermectin, treats lymphatic filariasis and river blindness, which are parasites that have plagued humans for centuries and currently threaten 1.35 billion people around the world. Developing drugs to treat infectious diseases and making them available to the often-impoverished people who need them is extremely difficult. But because of a breakthrough and an unprecedented move by one of the largest pharmaceutical companies in the world, these diseases might soon be eradicated.

Satoshi Omura Kyodo/AP

Lymphatic filariasis, which can develop into a condition known as elaphantiasis, is a mosquito-transmitted worm that lodges in the lymphatic system, impairing it along with the victim’s immune system and kidneys. In the worst cases, the worm causes extreme swelling and disfigurement of tissue, limbs, and genital parts. According to the World Health Organization (WHO) 40 million people, mostly in African and South Asian countries are incapacitated by the disease, and shunned because of their disfigurement.

Onchocerciasis, or river blindness, is a worm spread through the bite of a blackfly, which breeds in rivers. The parasite produces larvae that move through human tissue, causing sever itching and skin rashes, as well as eye lesions, which can lead to severe visual impairment. An estimated 270,000 people are currently blinded by the disease. The vast majority of people at-risk live in Africa, where it has taken a huge economic toll on rural communities, which have had to move away from rivers to less productive land in order to avoid the disease.

William Campbell Mary Schwalm/AP

In the late 1970s, Satoshi Omura, a scientist at the Kitasato Institute in Tokyo found a component of a soil-dwelling bacteria (that’s right, he literally found it in the dirt) called Streptomyces that was very effective at killing parasites. He then sent cultures of this bacteria to William Campbell in New Jersey who worked for Merck & Co., the fourth largest pharmaceutical company in the world. There, Campbell successfully developed a drug called ivermectin from a compound in the bacteria culture. The discovery was a huge pharmaceutical breakthrough and the drug was determined to be extremely safe for humans and easily distributed.

But, as with many infectious disease drugs, the vast majority of people who needed it lived in the developing world and could not afford it.

What happened next was unprecedented.

In 1987, Merck announced it would partner with the WHO and donate Mectizan, the drug’s brand name, to any country who requested it for as long as they needed it. Before this, no large pharmaceutical company had ever given away a drug they developed to eradicate a disease. At a news conference after Merck’s announcement, the late Massachusetts senator Ted Kennedy said, “Merck’s gift to the World Health Organization is more than a medical breakthrough–it is truly a triumph of the human spirit.”

Since 1987, the Mectizan Donation Program has given out more than a billion treatments for onchoceriasis and lymphatic filariasis to people in 33 countries (in the late ’90s GlaxoSmithKline contributed another drug for lymphatic filariasis to the program). As a result, the transmission of onchoceriasis has been stopped in many countries. Last year Ecuador became the second affected country, after Colombia, to entirely eradicate the disease. Lymphatic filariasis cases have dramatically decreased, as well. The WHO forecasts that both diseases could be eliminated by 2020.

Omura and Campbell were awarded the Nobel Prize in medicine for their work.

The Nobel committee said ivermectin’s importance was “immeasurable” for the health of many in the world’s poorest regions.

“Treatment is so successful that these diseases are on the verge of eradication, which would be a major feat in the medical history of humankind,” the committee said.

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This Company Gave Away a Drug That Just Won the Nobel Prize and Helped Millions

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