Tag Archives: disease

Antibiotics Are Spreading Like Crazy—and a Lot of Them Are About to Stop Working

by HiltonXocsd Posted on September 19, 2015

Mother Jones

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In 1945, Sir Alexander Fleming won a Nobel Prize for his discovery of penicillin, which transformed modern medicine. Later that year, the bacteriologist issued a prescient warning: The miracle medicine could one day come with dangerous side effects. If antibiotics were overused, he told the New York Times, bacteria would develop resistance and spur a new generation of bugs impervious to the drugs’ power.

In the last 60 years, Fleming’s advice has gone largely unheeded. Antibiotic consumption continues to grow even as health officials around the world sound the alarm over rising numbers of resistant bacteria. Now, a new report from the Center for Disease Dynamics, Economics and Policy (CDDEP), a multidisciplinary research organization, paints a harrowing picture of where we stand in the arms race against antibiotic resistance. The main finding is grim: Antibiotic consumption rose by 30 percent between 2000 and 2010 and is expected to swell further as demand for drugs and mass-produced meat products grow around the world.

“Antibiotic resistance is now clearly a problem in both the developed world and developing countries,” coauthor Ramanan Laxminarayan told National Geographic. “Things are about to get a lot worse before they get better.”

With the report, CDDEP also launched an interactive data visualization that shows antibiotic use from 69 countries. Additional charts also show antibiotic resistance rates of 12 different types of bacteria. For example:

One reason for the rising rates of resistance: Many developing countries that now have access to affordable antibiotics do not yet have the infrastructure to regulate them. The report highlights that 80 percent of antibiotics are consumed in communities and not in hospitals, and are often not prescribed by doctors. Many of the drugs being used are intended only for emergency cases. As Maryn McKenna reported in National Geographic:

Troublingly, that rising consumption worldwide takes in the most precious last-ditch drugs. Carbapenem use rose by 40 percent between 2000 and 2010, and the use of the very last-resort drug class polymixins rose by 13 percent. Sales of those drugs are rising fastest in India, Pakistan and Egypt, and many of those sales are retail, outside countries’ healthcare systems.

According to the Centers for Disease Control and Prevention, of the roughly 2 million people in the United States afflicted every year with illnesses caused by antibiotic-resistant bacteria, 23,000 of them will die. These illnesses cost around $20 billion each year, and lead to an additional $35 billion in productivity losses.

In response to the imminent and growing threat of antibiotic resistance, this year, the White House launched the National Action Plan for Combating Antibiotic-Resistant Bacteria, which aims to cut down on overuse in the next five years. While it does offer a promising framework for better practices in health care, as my colleague Tom Phillpot reports, regulations fall short in one of the key areas of antibiotic overuse: agriculture. The meat industry consumes an unbelievable 80 percent of all antibiotics sold in the United States.

The Food and Drug Administration’s voluntary guidelines advise against the use of antibiotics for animal growth—but the industry continues to exploit regulatory loopholes and administer growing amounts of antibiotics to the animals we eat.

Worldwide, according to the report, more than 63,000 tons of antibiotics were given to livestock in 2010, and this number is only expected to grow. Over the next 15 years, as demand for meat grows around the world and small scale farms switch to mass production to keep up, animal consumption of antibiotics is projected to increase by 67 percent.

While the outlook on growing antibiotic use and the likelihood of increased resistance seems grim, the authors of the report offer six strategies that could help curb the issues before they get worse:

Reduce the need for antibiotics through improved water, sanitation, and immunization
Improve hospital infection control and antibiotic stewardship
Change incentives that encourage antibiotic overuse and misuse to incentives that encourage antibiotic stewardship
Reduce and eventually phase out subtherapuetic antibiotic use in agriculture
Educate and inform health professionals, policymakers, and the public on sustainable antibiotic use
Ensure political commitment to meet the threat of antibiotic resistance

Earlier this year, the World Health Organizations’ governing body, the World Health Assembly, called for its member countries to adopt policies that will curb antibiotic use by 2017. The report’s authors hope their findings will lead to stronger stewardship around the world.

“With support from WHO and the international community, this resolution could catalyze change—or, like similar resolutions over the past decade, it may be ignored,” they write. “The evidence in this report, documenting the seriousness of the problem and offering a successful approach to country level action, supports both the urgency and the feasibility of making progress in conserving antibiotic effectiveness.”

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Antibiotics Are Spreading Like Crazy—and a Lot of Them Are About to Stop Working

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Mutant Super Lice May Be Coming to a School Near You

by ReganV32die Posted on August 26, 2015

Mother Jones

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With the summer closing out its final weeks, kids around the US are packing up their book-bags, collecting their colored pencils and heading back to school. But, amidst the excitement, parents have a new worry: super lice.

Lice infestations typically affect up to 12 million kids ages 3 to 11 each year. But, in 25 states, the blood-eating parasites that make their homes in hair and are commonly spread in classrooms have become resistant to most over-the-counter treatment methods, according to a new study.

Lice populations in the states in pink have developed a high level of resistance to some of the most common treatments. Kyong Yoon, Ph.D.

“We are the first group to collect lice samples from a large number of populations across the U.S.,” researcher Kyong Yoon said in a statement published with the study, which was presented at the American Chemical Society. “What we found was that 104 out of the 109 lice populations we tested had high levels of gene mutations, which have been linked to resistance to pyrethroids.”

Pyrethroids, insecticides that can be bought in FDA-approved shampoo-form from a pharmacy, have long been go-to treatments for lice infestations.

Overuse, Yoon found, could be to blame for the loss in the insecticides’ effectiveness — and the problem has been growing for years. While the latest study used the largest survey of the data on lice in the United States, the super lice problem was identified back in the 1990’s.

Still, Yoon’s study—and the alarm that resulted from it—has been scrutinized by other scientists who say it’s not time to panic yet. While Yoon concluded many of the lice had genetic mutations that made them less sensitive to the insecticides, traditional treatment methods may still be enough to kill them. As Medpage Today reports:

“The relationship between clinical and genetic resistance is still debated,” said Rémy Durand, PharmD, PhD, HDR, a researcher in the Department of Parasitology and Mycology at Hôpital Avicenne in Paris, France. While kdr mutations are well known for their effects on insecticide resistance in many insect species, Durand pointed out that some limited studies have actually reported that the presence of these “mutant alleles” in lice did not correlate with clinical failure.

Should we fear the rise of mutant lice? The good news, health officials report, is that the critters aren’t dangerous and they don’t spread disease. The Centers for Disease Control and Prevention still recommends the over-the-counter treatments, followed by prescription-strength remedies if that doesn’t knock them out.

Still, Yoon’s findings serve as an important warning that extends beyond louse-removal:

“If you use a chemical over and over, these little creatures will eventually develop resistance,” Yoon says. “So we have to think before we use a treatment.”

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Mutant Super Lice May Be Coming to a School Near You

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Ben Carson: Abortion Is the No. 1 Killer of Black People

by JeannaPTLP Posted on August 14, 2015

Mother Jones

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On Thursday, Ben Carson, a neurosurgeon and Republican presidential candidate, double downed on his recent assertion that Planned Parenthood founder Margaret Sanger used abortions as a population control tool in order to try and destroy the black population.

When asked by Fox News if he stood by his eyebrow-raising comments, Carson answered unequivocally, “Absolutely. No question about it.”

“Anybody can easily find out about Margaret Sanger and what kind of person she was and how she was a strong advocate of eugenics,” he explained. “She wrote articles about eugenics and believed that certain members of the population weakened the population and was not enamored of black people. And it is quite true that the majority and plurality of their clinics are in minority neighborhoods.”

But Carson then brought the discussion up to 2015. “It brings up a very important issue and that is do those black lives matter?” Carson added. “The number one cause of death for black people is abortion. I wonder if maybe some people might at some point become concerned about that and ask why is that happening and what can be done to alleviate that situation. I think that’s really the important question.”

According to the Centers for Disease Control, heart disease is the number one cause of death for African Americans.

His attack on the women’s health organization comes the same week that it was revealed Carson used fetal tissues to conduct medical research—a practice that has come under fire in recent weeks after an anti-abortion group published a string of a heavily-edited video footage appearing to capture Planned Parenthood officials discussing the sale of fetal tissues.

Despite his very vocal anti-abortion criticism, Carson defended his past research on aborted fetuses and argued that there was no inconsistency with this and his continued attacks on Planned Parenthood. “Killing babies and harvesting tissue for sale is very different than taking a dead specimen and keeping a record of it,” he said. “Which is exactly the source of the tissue used in our research.”

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Ben Carson: Abortion Is the No. 1 Killer of Black People

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Sorry, Foodies: We’re About to Ruin Kale

by AnnieQ01jltz Posted on July 15, 2015

Mother Jones

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How hipster is kale? For $28, Urban Outfitters will sell you a kale t-shirt. To prep for a big blizzard in early 2015, residents of a trendy Brooklyn section cleaned out the kale bins of their neighborhood Whole Foods. And what would the juicing craze be without it?

But today’s kale-fixated juice-heads may doing themselves a disservice.

That’s a possibility raised by an article in Craftsmanship magazine by Todd Oppenheimer. The piece doesn’t establish a definitive link between heavy kale consumption and any health problem, but it does raise the question of whether too much of even a highly nutritious food like kale can have unhappy side effects.

The article focuses on an alt-medicine researcher and molecular biologist named Ernie Hubbard, who began to notice an odd trend among some of his clinic’s clients in California’s Marin County, a place known for its organic farms, health-food stores, and yoga studios. Extremely health-conscious people were coming into to complain of “persistent but elusive problems”: “Chronic fatigue. Skin and hair issues. Arrhythmias and other neurological disorders. Foggy thinking. Gluten sensitivity and other digestive troubles. Sometimes even the possibility of Lyme Disease.”

Hubbard began to find detectable levels of a toxic heavy metal called thallium in patients’ blood samples—at higher-than-normal leves—as well as in kale leaves from the region. Meanwhile, “over and over,” he found that patients complaining of symptoms associated with low-level thallium poisoning—fatigue, brain fog, etc.—would also be heavy eaters of kale and related vegetables, like cabbage.

And he found, in the form of this 2006 peer-reviewed paper by Czech researchers, evidence that kale is really good at taking up thallium from soil. The paper concluded that kale’s ability to accumulate soil-borne thallium is “very high and can be a serious danger for food chains.” And here’s a peer-reviewed 2013 paper from Chinese researchers finding similar results with green cabbage; a 2015 Chinese study finding green cabbage is so good at extracting thallium from soil that it can be used for “phytoremediation”—i.e., purifying soil of a toxin—and a 2001 one from a New Zealand team finding formidible thallium-scrounging powers in three other members of the brassica family: watercress, radishes, and turnips.

Now, just because kale and other brassicas can effectively take up thallium from soil doesn’t mean that they always contain thallium. The metal has to find its way into soil first. It exists at low levels in the Earth’s crust, and the main way it gets concentrated at high enough levels to cause worry is through “nearby cement plants, oil drilling, smelting, and, most of all, in the ash that results from coal burning,” Oppenheimer reports. The researcher he profiled, Hubbard, has so far not succeeded in nailing down the source of the thallium that he found in his kale samples.

And there’s also the question of quantity. One of Hubbard’s patients with heightened thallium levels in her urine and mild symptoms of thallium poisoning ate so much cabbage over the years that she called herself the “cabbage queen.” When she “cut way back” on her favorite vegetable, she tells Oppenheimer, her thallium levels dropped, and her symptoms improved.

Where does all of this evidence, anecdotal and otherwise, leave us—beyond the need of much more research on US-grown kale? There’s nothing here that makes me want to stop eating brassicas, probably my favorite vegetable genus and one undeniably loaded with many valuable nutrients.

But it does make me wary of downing brassicas daily at great quantities over extended periods, the way some people may be doing as part of the juice craze. This recipe for “mean green juice,” for example, calls for six to eight kale leaves in a single serving—much more than most of us would consume in a side dish of sautéed kale. In all great things—wine, butter, ice cream, even kale—moderation makes sense.

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Sorry, Foodies: We’re About to Ruin Kale

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John Boehner: "I’m Sorry, but a Gun Is Not a Disease"

by ceramide-capsules1 Posted on July 2, 2015

Mother Jones

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Last week, after a shooter killed nine parishioners at a historic black church in Charleston, South Carolina, the House Appropriations Committee quietly voted on a bill to effectively block any funding for the Centers for Disease Control and Prevention to research the causes of gun violence in America. At a press conference last Thursday, a reporter from WNYC’s The Takeaway asked House Speaker John Boehner about the committee’s vote, which was just part of a decades-long string of Republican rejections of official efforts to study gun violence. Boehner responded with this familiar argument:

Listen, the CDC is there to look at diseases that need to be dealt with to protect the public health. I’m sorry, but a gun is not a disease. And guns don’t kill people; people do. And when people use weapons in a horrible way, we should condemn the actions of the individual, not blame the action on some weapon. Listen, there are hundreds of millions of weapons in America. They’re there. And they’re going to be there. They’re protected under the Second Amendment. But people who use weapons in an inappropriate or illegal way ought to be dealt with severely.

In the wake of the mass shooting in Charleston, President Obama expressed frustration with Congress for not passing gun safety reforms, and underscored the immense and untold cost of gun violence. “Whether it’s a mass shooting like the one in Charleston, or individual attacks of violence that add up over time, it tears at the fabric of the community,” Obama told a room full of mayors two weeks ago. “It costs you money, and it costs resources. It costs this country dearly.”

Read more about the staggering costs of gun violence in this recent Mother Jones investigation.

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John Boehner: "I’m Sorry, but a Gun Is Not a Disease"

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Why a German Court Just Ordered A Vaccine Skeptic to Pay $100K

by DixieHarden Posted on March 13, 2015

Mother Jones

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Four years ago, vaccine-skeptical German biologist Stefan Lanka posed a challenge on his website: Prove to him that measles is, in fact, a virus. To the first person who could do that, he promised a whopping 100 thousand Euros (about $106,000).

Despite loads of long-standing medical evidence proving the existence of the measles virus, Lanka believes that measles is a psychosomatic disease that results from trauma. “People become ill after traumatic separations,” he told a German newspaper.

German doctor David Barden took him up on the challenge. Barden gathered six separate studies showing that measles is indeed a virus. Lanka dismissed his findings.

But today, a district court in southern Germany found that Barden’s evidence provides sufficient proof to have satisfied Lanka’s challenge. Which means Lanka now has to cough up the promised cash.

This issue has taken on new urgency due to a measles epidemic in Berlin that began in October. Health officials announced last Friday that 111 new cases had been reported in the previous week, bringing the total number to 724. The majority of those affected are unvaccinated; last month an 18-month-old died of the disease.

Lanka said he plans to appeal the court’s decision.

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Why a German Court Just Ordered A Vaccine Skeptic to Pay $100K

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White Men Are Overdosing on Heroin at a Record Rate

by Juliane84J Posted on March 9, 2015

Mother Jones

A decades-long surge in heroin use has left behind a trail of overdose victims. A Centers for Disease Control and Prevention report released this week found that the number of heroin overdoses quadrupled from 1,842 in 2000 to 8,257 in 2013—with a significant boost among people between the ages of 18 and 44, particularly white men.

Dr. Len Paulozzi, a medical epidemiologist who studies drug overdoses at the CDC’s Injury Center, says that both the growing availability of heroin nationwide and the shift among prescription drug users to heroin use may have contributed to the dramatic rise in deaths. “Thirty years ago, people snorting heroin never used OxyContin or Vicodin before” using heroin, says Paulozzi, who did not contribute to the CDC report. But now the drug’s abusers start with prescription drugs, he says, turning these meds into gateway drugs. A National Survey on Drug Use and Health study found that heroin abuse was 19 times higher among people who had previously abused pain relievers.

The increase in overdoses follows a federal crackdown on prescription painkillers, beginning toward the end of the Clinton era and lasting through the Bush administration, that resulted in a rash of arrests for illegal use during the mid-2000s. While the rate of deaths involving prescription painkillers like OxyContin appears to have leveled off, heroin overdoses have risen 348 percent. Most of the deaths occurred after 2010. That year, a new tamper-resistant form of Oxy hit the market, making it less potent and harder to abuse.

The rate of heroin deaths accelerated among people between the ages of 18 and 24, from 0.8 deaths per 100,000 people in 2000 to 3.9 deaths per 100,000 in 2013. For people between 25 and 44 years old, the rate jumped from 1.3 deaths per 100,000 people in 2000 to 5.4 per 100,000 in 2013. Among young and middle-aged white people, that death rate reached 7.0 per 100,000 by 2013.

The CDC report also highlighted the stark gender and regional disparities among those who overdose. Deaths among men from heroin overdoses were four times higher than those among women between 2000 and 2013. While heroin overdoses increased throughout the country, the greatest number occurred in the Northeast and Midwest. In those regions, particularly near cities, the Justice Department observed the illicit drug as a rising threat—especially given the reported spike in the use of fentanyl, a synthetic opioid some 30 times more potent than heroin.

According to the Washington Post, the Justice Department predicted the emerging trend in 2002: “As initiatives taken to curb the abuse of OxyContin are successfully implemented, abusers of OxyContin…also may begin to use heroin, especially if it is readily available, pure, and relatively inexpensive.” A flood of heroin from Mexico, the world’s third-largest opium producer, also factored into the drug’s availability in the United States. In 2013, the Drug Enforcement Administration seized 2,196 kilograms of powder and black tar at the US-Mexico border, a nearly 160 percent bump from 2009.

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White Men Are Overdosing on Heroin at a Record Rate

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GOP Chair of the Science and Tech Subcommittee: I Didn’t Vaccinate My Kids

by Veola28Njffo Posted on February 27, 2015

Mother Jones

Rep. Barry Loudermilk, a Georgia Republican who recently became the chair of a key congressional subcommittee on science and technology, didn’t vaccinate most of his children, he told a crowd at his first town hall meeting last week.

Loudermilk was responding to a woman who asked whether he’d be looking into (discredited) allegations that the Centers for Disease Control and Prevention (CDC) had covered up information linking vaccines to autism. He responded with a rather unscientific personal anecdote: “I believe it’s the parents’ decision whether to immunize or not…Most of our children, we didn’t immunize. They’re healthy.”

Loudermilk’s comment sparked sharp criticism, including from Rick Wilson, a prominent Republican strategist who called for the congressman’s resignation.

Having “healthy,” unvaccinated kids does not mean that they aren’t at risk, or that they won’t put others at risk later if they become infected. So far this year, there have been 154 cases of measles and three outbreaks; one outbreak sickened 86 people and landed 30 babies in home isolation. The disease spreads rapidly, afflicting not only those who lack immunization due to parental choice, but also those who haven’t been vaccinated because they are immunocompromised. Prior to the advent of the measles, mumps, and rubella (MMR) vaccine, measles was responsible for up to 500 deaths in the United States every year. Due to low vaccination rates, 2014 saw the most confirmed cases of measles since 2000, when the CDC had declared the illness all but eliminated in the United States.

If Loudermilk is unconcerned about the potential health effects of once-common diseases, he may want to note the economic repercussions. The 107 confirmed cases of measles during the 2011 outbreak cost taxpayers $5.3 million to contain. Rigorous scientific research—including the 2004 CDC study cited by Loudermilk’s constituent—has shown that theories about a supposed connection between vaccines and autism are unfounded.

The CDC study in question looked at children with and without autism to find out if there was any difference in their rates of MMR vaccination. The researchers found none. The so-called “cover-up” originated from a secretly recorded and cherry-picked conversation between William Thompson, a senior scientist at the CDC, and Brian Hooker of Focus for Health, an organization that seeks “to put an end to the needless harm of children by vaccination and other environmental factors.” In the conversation, Thompson allowed that among African-American boys, in a small subset of children studied, the incidence of autism was higher for those who were vaccinated than those who were not. That statement landed in a wildly misleading video released on YouTube produced by Hooker and Andrew Wakefield, a British researcher whose medical license was revoked in 2010. A year later, a journal that published Wakefield’s paper linking autism and vaccines determined his findings were fraudulent.

We’ve reached out to Rep. Loudermilk for comment.

Watch the full press conference, via Georgiapolitics.org, here. (Vaccines enter the fray at 1:26:00)

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GOP Chair of the Science and Tech Subcommittee: I Didn’t Vaccinate My Kids

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Scientists Bash EPA’s Take On Burning Wood For Power

by NapoleoGoold Posted on February 13, 2015

green4us

Is biomass really carbon-neutral? Scott Wylie/Flickr A group of 78 scientists is criticizing an Environmental Protection Agency memo they say may dramatically undermine President Barack Obama’s directive to cut planet-warming emissions. In a letter to EPA Administrator Gina McCarthy, a group that includes climate scientists, engineers, and ecologists criticizes a November 2014 EPA policy memo that discounts emissions generated by burning biomass, including plants, trees, and other wood products known as sources of biogenic carbon dioxide. Critics said they fear the memo shows how biomass might be treated under the EPA’s forthcoming Clean Power Plan, which will set the first regulations on greenhouse gas emissions from power plants. The EPA is expected to finalize those regulations by summer. The EPA memo states that using biomass as a source of power is “likely to have minimal or no net atmospheric contributions of biogenic [carbon dioxide] emissions” as long as the biomass is produced with “sustainable forest or agricultural practices.” It also suggests that states will be able to increase the use of biomass in power plants in order to meet the limits set in the Clean Power Plan. The biogenic energy framework was the subject of a recent article in Politico magazine, which found that the interpretation “could promote the rapid destruction of America’s carbon-storing forests.” Read the rest at The Huffington Post.

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Scientists Bash EPA’s Take On Burning Wood For Power

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Scientists Bash EPA’s Take On Burning Wood For Power

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Scott Walker’s Budget Includes $250,000 To Study ‘Wind Energy System-Related Health Issues’

by Myrna Posted on February 13, 2015

Previous studies have found no link between wind farms and increased health problems. Gateway Technical College/Flickr The two-year, $68 billion budget proposal Wisconsin Gov. Scott Walker unveiled Tuesday includes a request for $250,000 to study the health impacts of wind turbines. Page 449 of the budget proposal includes a recommendation from the governor “directing the commission to conduct a study on wind energy system-related health issues.” The request states that a report should be submitted to the governor and legislature within a year after the budget goes into effect. “The request for a Wind Energy Health Issues Study was included with the intent to provide the Public Service Commission with comprehensive information to consider as they receive requests for future wind energy projects,” said Laurel Patrick, Walker’s press secretary, in a statement to The Huffington Post. Read the rest at The Huffington Post. Visit site – Scott Walker’s Budget Includes $250,000 To Study ‘Wind Energy System-Related Health Issues’

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Scott Walker’s Budget Includes $250,000 To Study ‘Wind Energy System-Related Health Issues’

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