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The Disordered Mind – Eric R. Kandel

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The Disordered Mind

What Unusual Brains Tell Us About Ourselves

Eric R. Kandel

Genre: Life Sciences

Price: $14.99

Publish Date: August 28, 2018

Publisher: Farrar, Straus and Giroux

Seller: Macmillan


Eric R. Kandel, the winner of the Nobel Prize in Physiology or Medicine for his foundational research into memory storage in the brain, is one of the pioneers of modern brain science. His work continues to shape our understanding of how learning and memory work and to break down age-old barriers between the sciences and the arts. In his seminal new book, The Disordered Mind , Kandel draws on a lifetime of pathbreaking research and the work of many other leading neuroscientists to take us on an unusual tour of the brain. He confronts one of the most difficult questions we face: How does our mind, our individual sense of self, emerge from the physical matter of the brain? The brain’s 86 billion neurons communicate with one another through very precise connections. But sometimes those connections are disrupted. The brain processes that give rise to our mind can become disordered, resulting in diseases such as autism, depression, schizophrenia, Parkinson’s, addiction, and post-traumatic stress disorder. While these disruptions bring great suffering, they can also reveal the mysteries of how the brain produces our most fundamental experiences and capabilities—the very nature of what it means to be human. Studies of autism illuminate the neurological foundations of our social instincts; research into depression offers important insights on emotions and the integrity of the self; and paradigm-shifting work on addiction has led to a new understanding of the relationship between pleasure and willpower. By studying disruptions to typical brain functioning and exploring their potential treatments, we will deepen our understanding of thought, feeling, behavior, memory, and creativity. Only then can we grapple with the big question of how billions of neurons generate consciousness itself.

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The Disordered Mind – Eric R. Kandel

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Did Climate Change Cause Russia’s Deadly Anthrax Outbreak?

Scientists are investigating whether melting permafrost has unleashed the bacteria. A photomicrograph of Bacillus anthracis bacteria, the bacteria that causes anthrax. CDC This story was originally published by the Guardian. A 12-year-old boy in the far north of Russia has died in an outbreak of anthrax that experts believe was triggered when unusually warm weather caused the release of the bacteria. The boy was one of 72 nomadic herders, including 41 children, hospitalized in the town of Salekhard in the Arctic Circle, after reindeer began dying en masse from anthrax. Five adults and two other children have been diagnosed with the disease, which is known as “Siberian plague” in Russian and was last seen in the region in 1941. More than 2,300 reindeer have died, and at least 63 people have been evacuated from a quarantine area around the site of the outbreak. “We literally fought for the life of each person, but the infection showed its cunning,” the Yamal governor, Dmitry Kobylkin, told the Interfax news agency. “It returned after 75 years and took the life of a child.” The tabloid LifeNews reported that the boy’s grandmother died of anthrax at a nomad camp last week. Authorities said the outbreak was linked to climate change. For the past month, the region has been experiencing abnormally high temperatures that have reached 95 Fahrenheit. Anthrax spores can survive in frozen human and animal remains for hundreds of years, waiting to be released by a thaw, according to Alexei Kokorin, head of WWF Russia’s climate and energy program. “Such anomalous heat is rare for Yamal, and that’s probably a manifestation of climate change,” he said. Average temperatures in Russia have increased by 0.43 degrees Celsius (0.77 degrees F) in the past 10 years, but the rise has been more pronounced in areas of the far north. The warmer climate has begun thawing the permafrost soil that covers much of Russia, including cemeteries and animal burial grounds. Thawing permafrost has also led to greater erosion of river banks where nomads often buried their dead, Kokorin said. “They didn’t bury deep because it’s hard to dig deep in permafrost,” he explained. According to custom, the Nenets tribe often inters its dead in a wooden coffin on open ground. The disease from thawing human and animal remains can get into groundwater that people then drink. The boy in Salekhard died from the intestinal form of the disease, which typically results in fever, stomach pain, diarrhea and vomiting. Other reports said a local cemetery was suspected, or infected venison. Three unusual sinkholes were discovered on the Yamal peninsula in 2014, a phenomenon that many scientists also tied to climate change. Thawing permafrost could have allowed gas in the ground to explode, they said. This summer, researchers have filmed grassy ground on an island off the Yamal peninsula that appeared to bounce under their feet. The phenomenon was likely caused by “bubbles” of methane and carbon dioxide, they said. View post:  Did Climate Change Cause Russia’s Deadly Anthrax Outbreak? ; ; ;

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Did Climate Change Cause Russia’s Deadly Anthrax Outbreak?

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Paris Talks May Set an Ambitious—and Meaningless—Goal on Climate Change

Based on current policies, there is no hope of limiting warming to 1.5 degrees. Kekyalyaynen/Shutterstock Compared to the conferences that came before it, Paris is going smoothly. So smoothly, relatively speaking, that there is still some sense of positivity amid the last-minute scrambling. As if to emphasize just how optimistic world leaders are feeling, negotiators released a draft agreement on Thursday that actually puts forward a more ambitious goal for global warming than many had expected going into the conference. The draft text, released after marathon, around-the-clock negotiations, defines the purpose of the agreement as holding “the increase in the global average temperature to well below 2 °C above pre-industrial levels and to pursue efforts to limit the temperature increase to 1.5 °C, recognizing that this would significantly reduce risks and impacts of climate change.” The language is a compromise—an acknowledgement that some people will suffer more than others at 1.5 degrees of warming that doesn’t go so far as to set a new target. But the real problem is it’s an empty gesture, serving as a reminder that when politicians aren’t on track to meet one of their climate goals, they will offer an even less realistic one. Five years ago, nearly 200 countries agreed in Cancun to set a ceiling for climate change at 2 degrees Celsius above pre-industrial averages. That target was always an aspirational red line: Today, the world is already 1 degree above pre-industrial averages and on track to blow past 2 in the next 20 years. At the same time, climate scientists and vulnerable nations have argued that anything above 1.5 degrees Celsius, and certainly above 2, will be devastating. The effects of climate change are disparate, so the world’s poor tend to get hit by its consequences long before the rich. Read the rest at The New Republic. Visit site:  Paris Talks May Set an Ambitious—and Meaningless—Goal on Climate Change ; ; ;

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Paris Talks May Set an Ambitious—and Meaningless—Goal on Climate Change

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The Ugly Truth Lurking Behind the Climate Talks

As a climate deal nears, power players want accountability (just not for themselves). US Secretary of State John Kerry and UN Secretary General Ban Ki-moon meet on the sidelines of the Paris climate negotiations. Mandel Ngan/Pool/AP LE BOURGET, France—When I meet new people here, the first question I usually get is a variation on, “Are these your first climate talks?” What they want to know is if I’m an expert like them—if I know the jargon, the unwritten rules, the backstories of who’s been fighting who since Kyoto ’97. The answer is, yes, these are my first talks. And that’s made for some humbling learning curves (look, “ADP” and “informal informal” aren’t exactly self-defining terms). But the good part is that I got to come here with the outsider’s perspective of someone who’s spent more time covering disaster, social upheaval, and response, particularly in Haiti, the country ranked as the third-most affected by climate change so far. In other words, I’ve seen a few things—things that leave me with a question right at the center of what is likely to be the major battle in the final stage of these talks. I think everyone gets the importance of money and power at these negotiations by now. The operating assumption is that rich countries who’ve benefited most from carbon emissions will pay something to alleviate the effects of global warming on the poor, while helping the new major polluters, such as India, get off carbon before they burn us past the point of no return. Read the rest at The New Republic. Link:  The Ugly Truth Lurking Behind the Climate Talks ; ; ;

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The Ugly Truth Lurking Behind the Climate Talks

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Obama Just Called Saving the Planet an “Act of Defiance” Against Terror

As major UN talks kick off in Paris, the president acknowledged America’s role in causing global warming. A major two-week summit on climate change opened on Monday in Paris, and President Barack Obama was there to urge world leaders to push for a strong international agreement to slow global warming. In his speech (video above), the president also offered a rebuke to the terrorists behind the November 13 attacks in the French capital that left 130 people dead. The summit, he said, is “an act of defiance that proves nothing will deter us from building the future we want for our children.” Obama acknowledged America’s unique responsibility for ensuring success at the talks, which are designed to produce an unprecedented agreement between nearly 200 nations to reduce greenhouse gas emissions and prepare for the impacts of climate change. It’s the first time nations have tried to reach that goal since the last major climate summit, in 2009 in Copenhagen, crumbled over disagreements between the United States, China, and developing nations. In his second term, Obama has sought to make action on climate change a central part of his legacy; a strong agreement in Paris would be a vital component to that. “I’ve come here personally, as the leader of the world’s largest economy and the second-largest emitter,” Obama said, “to say that the United States of America not only recognizes our role in creating this problem, we embrace our responsibility to do something about it.” Prior to the speech, Obama met privately with Chinese President Xi Jinping. The two leaders have worked closely over the last year to advance a joint climate agenda. Xi also gave a speech, in which he said it was “very important for China and the United States to be firmly committed to the right direction of building a new model of major country relations.” Obama’s remarks come a day after the White House announced a sweeping initiative to double public-sector investment in clean energy research and development from $5 billion to $10 billion by 2020. That new program, known as Mission Innovation, also includes more than a dozen major private-sector investors, including Bill Gates, Richard Branson, and Mark Zuckerberg. Finance for clean energy and for climate change adaptation is likely to be a major issue at the talks, as vulnerable nations in Africa, Southeast Asia, and elsewhere urge the United States and other major emitters to pony up more cash. At the last major climate summit in Copenhagen, countries agreed to raise $100 billion per year for a UN-administered climate adaptation fund. That goal is only about two-thirds met. Jump to original –  Obama Just Called Saving the Planet an “Act of Defiance” Against Terror ; ; ;

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A Massive Climate Summit Just Started in Paris. Here’s What You Need to Know.

Diplomats and scientists are descending on the French capital Monday. They’ll try to save the world. INTERPIXELS/Shutterstock On Monday, roughly 40,000 heads of state, diplomats, scientists, activists, policy experts, and journalists will descend on an airport in the northern Paris suburbs for the biggest meeting on climate change since at least 2009—or maybe ever. The summit is organized by the United Nations and is primarily aimed at producing an agreement that will serve as the world’s blueprint for reducing greenhouse gas emissions and adapting to the impacts of global warming. This is a major milestone in the climate change saga, and it has been in the works for years. Here’s what you need to know: What’s going on at this summit, exactly? At the heart of the summit are the core negotiations, which are off-limits to the public and journalists. Like any high-stakes diplomatic summit, representatives of national governments will sit in a big room and parse through pages of text, word by word. The final document will actually be a jigsaw puzzle of two separate pieces. The most important part is the Intended Nationally Determined Contributions (INDCs). These are commitments made individually by each country about how they plan to reduce their carbon footprints. The United States, for example, has committed to cut its greenhouse gas emissions 26 to 28 percent below 2005 levels by 2025, mostly by going after carbon dioxide emissions from coal-fired power plants. Nearly every country on Earth has submitted an INDC, together covering about 95 percent of global greenhouse gas emissions. (You can explore them in detail here.) The video below, from Climate Desk partner Grist, has a good rundown of how this all really works. The INDCs will be plugged in to a core agreement, the final text of which will be hammered out during the negotiations. It will likely include language about how wealthy nations should help pay for poor nations’ efforts to adapt to climate change; how countries should revise and strengthen their commitments over time; and how countries can critically evaluate each other’s commitments. While the INDCs are unlikely to be legally binding (that is, a country could change its commitment without international repercussions), certain elements of the core agreement may be binding. There’s some disagreement between the United States and Europe over what the exact legal status of this document will be. A formal treaty would need the approval of the Republican-controlled US Senate, which is almost certainly impossible. It’s more likely that President Barack Obama will sign off on the document as an “executive agreement,” which doesn’t need to go through Congress. Meanwhile, outside the negotiating room, thousands of business leaders, state and local officials, activists, scientists, and others will carry out a dizzying array of side events, press conferences, workshops, etc. It’s basically going to be a giant party for the world’s climate nerds. But what about the terrorist attacks in Paris? Of course, all of this will be happening while the French capital is still reeling from the bombings and shootings that left 129 dead on November 13. Shortly after the attacks, French officials affirmed that the summit would still happen. But it will be tightly controlled, with loads of additional security measures. As my colleague James West has reported, many of the major rallies and marches that activists had planned will be canceled at the behest of French authorities. So the festive aspects of the summit are likely to be toned way down, with attention focused just on the formal events needed to complete the agreement. The summit could also direct a lot of attention to the links between climate change, terrorism, and national security. Is this actually going to stop climate change? Short answer, no. The latest estimate is that the INDCs on the table will limit global warming to about 2.7 degrees Celsius above pre-industrial levels. As I wrote in October, “That’s above the 2 degrees C (3.6 degrees F) limit scientists say is necessary to avert the worst impacts—but it’s also about 1 degree C less warming than would happen if the world continued on its present course.” No one expects that this summit will be the end of the battle to stop climate change. As technology improves and countries get more confident in their ability to curb greenhouses gases, they’ll be able to step up their action over time. That’s why it’s essential for the agreement to include a requirement for countries to do so. In any case, even if the whole world stopped burning all fossil fuels right now, warming from existing greenhouse gas emissions would continue for decades, so adaptation is also a crucial part of the agreement. Some environmentalists have criticized that incremental approach as not urgent enough, given the scale of the problem. They could be right. But the fact is that right now, there’s no international agreement at all. The Paris talks will lay an essential groundwork for solving this problem over the next couple of decades. And there’s a pretty good chance the talks will be successful. At the last major climate summit, in 2009 in Copenhagen, negotiations crumbled because officials couldn’t agree on a set of global greenhouse gas limits that would hold most countries to the same standard despite differences in their resources and needs. That’s why, this time around, the approach is bottom-up: Because countries have already worked out their INDCs, there’s no ambiguity about what they’re willing to do and no need to agree on every detail. Meanwhile, the mere existence of the talks has already spurred a wave of new investment in clean energy, new commitments from cities and states around the globe, and other actions that aren’t part of the core agreement. And the international peer pressure around the INDCs has already made it clear that simply ignoring climate change isn’t a realistic geopolitical option, even for countries like Russia or the oil-producing Gulf states. That’s a significant change from what would be happening in the absence of the talks. In other words, it’s safe to say that the Paris summit has already been somewhat successful, and now we have the opportunity to see how far that success can go. So everything is peaches and cream? Not quite. There are some big remaining questions about how much money the United States and other wealthy countries will commit to help island nations, Southeast Asia, sub-Saharan Africa, and other places that are highly vulnerable to global warming. The international community is still far short of its goal of raising $100 billion annually by 2020 to fund adaptation. The legal status of the agreement remains unclear. We don’t know whether countries can agree on a long-term target date (say, 2100) to fully cease all greenhouse gas emissions. And it’s unclear how much tension there will be between juggernauts such as the United States, China, and the 43-country-strong negotiating bloc of highly vulnerable developing nations. At Climate Desk, we’ll have an eye on all these questions, and more—both from the ground in Paris and from our newsrooms in the United States. So stay tuned. Originally posted here –  A Massive Climate Summit Just Started in Paris. Here’s What You Need to Know. ; ; ;

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A Massive Climate Summit Just Started in Paris. Here’s What You Need to Know.

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French Government Nearing Decision About Whether to Ban Climate Protests

We’ll know Wednesday or Thursday whether or not the big climate march in Paris will go ahead. A memorial for the victims killed in Friday’s attacks in Paris in front of the French Embassy in Berlin. Markus Schreiber/AP We learned yesterday that even after Friday’s terrorist attacks that killed 129 people in Paris, global warming activists are pushing to go ahead with large protests and civil disobedience in the French capital two weeks from now. On Tuesday morning, Paris time, representatives of a coalition of 130 environmental groups met with French Foreign Minister Laurent Fabius to argue that the rallies should be allowed to take place alongside the upcoming UN climate summit—and to hear the government’s security concerns. The climate negotiations “cannot take place without the participation or without the mobilizations of civil society in France,” read a statement released yesterday by Coalition Climat 21, an umbrella group of activists. But even after the meeting this morning, there remains plenty of doubt about which events will be canceled and which will be permitted to take place. Paris remains under a state of emergency, and French President Francois Hollande has said parliament should extend that state of emergency for another three months. Jamie Henn, a spokesperson for the US-based environmental group 350.org, told me Tuesday morning that the French authorities are nearing a decision on the main climate march, which had been scheduled to take place in the streets of Paris on November 29, the evening before the summit opens. That permitting decision, he says, should come from the French government either Wednesday or Thursday. “The coalition is pushing hard for it to move forward if safety can be maintained,” Henn said. Organizers had expected to draw around 200,000 to the rally, according to Reuters. Coordinated climate rallies in cities around the world are expected to continue. “We’re still waiting for the French authorities to tell us if they think the march in Paris, and other mobilization moments around the climate talks, can be made safe and secure,” said Jean-François Julliard, Executive Director for Greenpeace in France, according to a statement. “Huge numbers are predicted for the Paris gathering. We at Greenpeace want it to happen.” But additional protests in Paris, such as plans to block roads and form human chains at the Place de la République, scheduled for December 12, “are still under negotiation,” Henn said. While security officials are still mulling the big November 29 March, activists say that French authorities have been pressuring them to cancel the more aggressive actions planned for the end of the summit. Those December 12 events were “always planned as civil disobedience and never had permission, so it’s not really a matter of the government banning it or not,” Henn said. “But the French authorities have made it clear they don’t want it to go forward.” Despite that, says Henn, “we’re committed to finding a way to make a strong call for climate justice at the end.” One thing we do know: The large exhibition pavilion set up by the UN at the site of the summit for environmental groups, observers, and the general public—called the Climate Generations space—will be maintained, “but maybe with new access rules,” Henn said. This post has been updated with more specific details about the December 12 protests. Excerpt from –  French Government Nearing Decision About Whether to Ban Climate Protests ; ; ;

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French Government Nearing Decision About Whether to Ban Climate Protests

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This Map Shows Where the Next Clean Energy Gold Mine Is

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It’s an area half the size of Rhode Island. Shutterstock The desert in Southern California could be in for a climate-friendly makeover, after the Obama administration released its plans to develop more renewable energy projects on federally owned land. On Tuesday the Interior Department released the final version of a plan that would open up about half a million non-contiguous acres—half the size of Rhode Island—for projects such as wind and solar farms in the Mojave Desert and surrounding areas. It would also more than double the amount of land dedicated to protecting delicate desert ecosystems that are home to vulnerable species, including the desert tortoise. The Mojave Desert, which stretches across most of Southern California, is a potential gold mine for clean energy. Earlier this year, the world’s largest solar farm opened there, near Joshua Tree National Park. According to Interior, the desert and the its surrounding area have the sun and wind potential to support 20,000 megawatts of renewable projects, about equal to the amount of solar energy installed nationwide today. In announcing the plan, Secretary of the Interior Sally Jewell said that public lands will “play a key role” in helping the United States meet its goal of procuring 20 percent of its electricity from renewable sources (excluding large hydro dams) by 2030—up from about 7 percent now. But over the past few years, efforts to develop all that potential have sparked clashes between clean energy buffs and conservationists who don’t want to see pristine landscapes blanketed by vast arrays of solar panels. One pioneering project, the Ivanpah Lake solar farm, became a pariah after environmental groups said that it encroached on tortoise habitat and that its sunlight-concentrating panels were blasting superheated rays into birds’ flight paths and killing tens of thousands of them. Subsequent estimates put the death toll much lower, but the Ivanpah controversy underscored just how hard it can be for government planners to find common ground between competing environmental interests. The new plan (finalized in October but made public Tuesday) is meant to clear the air by painstakingly analyzing a 2 million-acre swath of Southern California and offering a comprehensive take on where to focus clean energy development. Scientists and planners from a host of agencies stockpiled research on wildlife, water, agriculture, historic and cultural sites, and other features in an effort to find spots that have high renewable energy potential with minimal environmental impact. In the map below, the pink and red areas are where the Bureau of Land Management recommends that private developers focus their efforts. Orange and blue hatching shows areas proposed for conservation: BLM Anyone who wants to build a wind or solar farm in these areas still has to go through the normal permitting process that any development on public land has to clear. But the plan is meant to help developers avoid headaches by showing them the areas that the feds have already decided are either not ecologically sensitive, or that are already too degraded to worry much about building in. That’s a departure from the previous modus operandi, in which federal officials made case-by-case decisions on each proposed project. “It’s a real change from how BLM has approached renewable energy development in the past,” said Erica Brand, California energy program director at the Nature Conservancy. The agency, she added, is “protecting desert landscapes by directing development to areas that are more degraded.” Similar reviews of private and state-owned land will be released over the next year. And you can bet that there will be plenty of interest from renewable energy companies. California has the country’s most favorable investment climate for renewable energy, according to Ernst & Young, and the state recently adopted the country’s most aggressive renewable energy target: 50 percent of its electricity mix by 2030. That’s up from 20 percent now. “The [Mojave] Desert has some of the most intact natural landscapes in the lower 48,” Brand said. “As we transition to cleaner energy sources, and work to meet our climate goals, we also have to keep those natural resources intact.”

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This Map Shows Where the Next Clean Energy Gold Mine Is

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This Map Shows Where the Next Clean Energy Gold Mine Is

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Indonesia Fires Seen From a Million Miles Away

Yikes. NASA Normally, I think pictures of Earth from space are among the most beautiful of all astronomical photos. Our home is gorgeous, especially when seen from afar. But Monday, NASA tweeted a picture of our world whose ugliness made me literally gasp when I understood what I was seeing. The photo above is from the Earth-observing DSCOVR satellite, which sits 1.5 million km (almost a million miles) over our planet, taking full-disk images every hour, which are then put online for the public to view. That shot was taken on Oct. 25 at 05:37 UTC. NASA put the picture on Twitter to point out the three tropical low systems developing in the Indian Ocean. Which is great, and very cool. But what caught my eye was the huge grayish hazy patch over Indonesia, over to the right a bit. Read the rest at Slate. From: Indonesia Fires Seen From a Million Miles Away ; ; ;

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Indonesia Fires Seen From a Million Miles Away

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Watch 2 GOP Presidential Candidates Call Out Their Party for Denying Science

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Watch 2 GOP Presidential Candidates Call Out Their Party for Denying Science

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